![]() The collagen and reticular fibers were stained by Masson and Gordon–Sweets, respectively. The IFP was measured using the wick-in-needle (WIN) method. VX2 tumor in rabbit was treated with ultrasound combined with microbubbles at different intensities. In this study, we aimed to elucidate the relationship between ultrasound combined with microbubble therapy and IFP, and the associated mechanism. Reducing tumor IFP might be developed as a novel approach in cancer therapy. There are several methods to decrease the IFP, such as normalizing blood vessel, decreasing hyaluronic acid and collagen fiber content in the extracellular matrix (ECM), and recovering lymphatic function. Interstitial fluid pressure (IFP) in tumor tissue is significantly higher than that in normal tissue, which reduces the effectiveness of therapeutic drugs. ![]() 3Department of Medical Ultrasound, Guangzhou Women and Children’s Medical Center, Guangzhou, China. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |